Statewide legal status
Florida lists psilocybin and psilocyn in Schedule I. Personal possession remains unlawful unless authorized.

FL legal and access quick reference
Reviewed on September 28, 2026 by iMD teamA concise, source-dated explanation of statewide law, regulated access, and the difference between state and local policy.
Laws and implementation can change quickly. This page is educational information, not legal advice.
Florida lists psilocybin and psilocyn in Schedule I. Personal possession remains unlawful unless authorized.
Florida has not created a statewide psilocybin service-center, medical-access, personal-use, dispensary, or retail program.
Florida’s 2025 §500.75 separately restricts transporting, importing, selling, furnishing, or giving away spores or mycelium capable of producing psilocybin- or psilocyn-containing mushrooms. That restriction does not create legal access.
For Fort Lauderdale, Hialeah, Jacksonville, Miami, Orlando, St. Petersburg, Tallahassee and Tampa, this Florida page is the appropriate quick-reference starting point because no separate municipal action was retained as a distinct local-policy guide. Local rules can change, so verify current official records.
Florida’s psychedelic research activity expanded in 2026. USF Health reported that its Department of Psychiatry and Behavioral Neurosciences is conducting clinical trials of psychedelic medicines, including a COMP360 psilocybin study for post-traumatic stress disorder. Federal clinical-trial records also list recruiting Florida sites for additional late-stage studies involving psilocybin or closely related investigational compounds. These studies operate under research protocols and do not change Florida’s general statewide access rules.
The statewide explanation above covers Fort Lauderdale, Hialeah, Jacksonville, Miami, Orlando, St. Petersburg, Tallahassee and Tampa. A separate page appears below only where a documented municipal action adds material local context.
This review uses Florida’s current controlled-substance statutes, the spores-and-mycelium provision, and current university and federal clinical-research sources. Research activity is listed separately because participation in an authorized study does not change general statewide access rules.
Florida lists psilocybin and psilocyn in Schedule I. Personal possession remains unlawful unless authorized. Florida has not created a statewide psilocybin service-center, medical-access, personal-use, dispensary, or retail program.
Florida has not created a statewide psilocybin service-center, medical-access, personal-use, dispensary, or retail program.
No. Local enforcement choices do not repeal state law, legalize commercial sales, or create a statewide access program.
Yes. USF Health reported active psychedelic-medicine research in 2026, including a COMP360 psilocybin study for PTSD, and federal trial records list recruiting Florida sites for additional investigational psilocybin or psilocin-related studies. Participation is limited to approved research protocols and eligibility requirements.
The product-site link provides product-format and business-policy information. It does not change the law described on this page or establish legal access in any jurisdiction.