Schedule I · possession unlawful
Missouri lists psilocybin and psilocyn in Schedule I. Knowing possession remains unlawful under §579.015.
MO legal and access quick reference
Reviewed on September 29, 2026 by iMD teamPsilocybin law and access in Missouri
A concise, source-dated explanation of statewide law, regulated access, and the difference between state and local policy.
Laws and implementation can change quickly. This page is educational information, not legal advice.
No enacted public access program
Missouri has no enacted personal-use, retail, dispensary, or statewide supervised-service program for psilocybin.
2026 therapeutic-use proposal advanced
HB 1717, combined with HB 1643, advanced through the Missouri House and received a Senate committee substitute in 2026. The proposal addressed limited therapeutic use, research, and investigational-treatment pathways involving psilocybin. It did not complete enactment, so it does not create current statewide access.
2026 Missouri psilocybin policy update
Missouri lawmakers gave substantial consideration to psilocybin-related therapeutic and research policy in 2026. HB 1717, combined with HB 1643, passed the House and moved through Senate committee work before being placed on the House informal calendar on May 7, 2026.
The legislation included limited therapeutic-use protections and changes to Missouri’s investigational-treatment framework involving psilocybin. Because the proposal did not complete the enactment process, it should be read as legislative progress rather than an operating statewide access program.
What local policy means
For Columbia, Kansas City, Springfield and St Louis, this Missouri page is the appropriate quick-reference starting point because no separate municipal action was retained as a distinct local-policy guide. Local rules can change, so verify current official records.
Cities covered by the Missouri guide
The statewide explanation above covers Columbia, Kansas City, Springfield and St Louis. A separate page appears below only where a documented municipal action adds material local context.
ColumbiaCovered in Missouri guide
Kansas CityCovered in Missouri guide
SpringfieldCovered in Missouri guide
St LouisCovered in Missouri guide
Sources used for this review
This page was checked against the controlling state statutes, enacted laws, agency records, and official bill histories listed below.
- Missouri Revised Statutes §195.017 — controlled schedules ↗
- Missouri Revised Statutes §579.015 — possession ↗
- Missouri House — HB 1717 official status ↗
- HCS HBs 1717 and 1643 — bill text ↗
- Missouri House — HB 1717 2026 status and actions ↗
- Missouri House — HB 1643 fiscal note and therapeutic-use provisions ↗
Common questions
Is psilocybin legal in Missouri?
No. Psilocybin and psilocyn remain Schedule I substances, and knowing possession remains unlawful.
Does Missouri have a regulated psilocybin access program?
No. The 2026 therapeutic-use and research proposal did not become law and creates no current retail, dispensary, personal-use, or statewide treatment access.
Do city policies change Missouri law?
No. A local enforcement-priority policy may affect municipal enforcement, but it does not legalize commercial sale, create statewide legality, or override federal law.
What changed in Missouri psilocybin policy in 2026?
HB 1717 and HB 1643 advanced a proposal involving limited psilocybin therapeutic use, research, and investigational-treatment pathways. The combined proposal advanced through both chambers’ legislative process but did not become law, so Missouri did not create a statewide psilocybin access program in 2026.
Continue at the right depth
The product-site link provides product-format and business-policy information. It does not change the law described on this page or establish legal access in any jurisdiction.