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Wisconsin · Schedule I · federal-track research active · no 2026 state bill

Wisconsin's psilocybin story is federal-track research, with the state legislature quiet.

Wisconsin runs an active federal-track psilocybin research footprint with no corresponding state-level legislative pathway. UW-Madison's Transdisciplinary Center for Research in Psychoactive Substances (TCRPS), led by Prof. Paul Hutson, runs FDA-authorised trials in psilocybin for major depressive disorder, psilocybin for opioid use disorder, MDMA for PTSD (in MAPS partnerships), and psilocybin safety studies. Usona Institute in Madison received one of three nationwide HHS pediatric/adult drug-development vouchers via April 2026 executive order (Compass Pathways and Transcend Therapeutics received the other two). At the state level, the 107th Legislature adjourned February 20, 2026 with no 2026 psilocybin bills filed. SB 727 (2023) died in the prior session. Schedule I status applies for all general possession.

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UW-MadisonTCRPS
UsonaHHS voucher
SB 727Died 2023
Feb 20 2026WI adjournment

Dual track

How a state runs major research with no state legislation

Wisconsin's policy posture is unusual: significant federal-track research density alongside near-total state-level legislative quiet. The two tracks operate in parallel without intersecting.

Federal-track research at UW-Madison and Usona Institute is moving. The Wisconsin Legislature's state track is quiet — no 2026 bill, no live committee work.

Federal track FDA INDs, HHS vouchers, federal grants
UW-Madison TCRPS Usona Institute HHS voucher (Apr 2026) Compass Pathways P3 MAPS MDMA-PTSD
State track Wisconsin Legislature, 107th session
SB 727 (2023) 2025-26 session Feb 20 2026 adjournment No 2026 bill filed

Why this shape

Federal research authority vs state legislative pathways

Psilocybin research operates on federal authority — FDA INDs, DEA Schedule I researcher registrations, federal grants. State legislation governs general access, not research conduct. Wisconsin's research density reflects its federal-track institutional strength (UW-Madison, Usona Institute), independent of state legislative posture.

Prof. Paul Hutson's TCRPS programme is a leading academic node in U.S. psilocybin research. The April 2026 HHS voucher to Usona Institute, alongside Compass Pathways and Transcend Therapeutics, makes Madison one of the three nationwide hubs for HHS-recognised drug development work.

3 cities

Where the policy and the people live

Common questions

Wisconsin psilocybin FAQ

Q · 01

Is psilocybin legal in Wisconsin?

No. Psilocybin is Schedule I under Wisconsin's Uniform Controlled Substances Act. General possession is a criminal offence. Federal-track research at UW-Madison TCRPS and Usona Institute operates on federal authority, not general access.

Q · 02

Has Wisconsin filed any psilocybin bill in 2026?

No. The 107th Wisconsin Legislature adjourned February 20, 2026 with no 2026 psilocybin bills having been filed. SB 727 (2023) died in the prior session and has not been refiled.

Q · 03

What is the Usona Institute voucher?

Usona Institute, a Madison-based research nonprofit, received an HHS pediatric/adult drug-development voucher via April 2026 executive order. It is one of three nationwide voucher recipients alongside Compass Pathways and Transcend Therapeutics. The voucher supports federally recognised drug-development work.

Q · 04

What does UW-Madison TCRPS do?

The Transdisciplinary Center for Research in Psychoactive Substances at UW-Madison School of Pharmacy, led by Prof. Paul Hutson, runs FDA-authorised trials including psilocybin for major depressive disorder, psilocybin for opioid use disorder, MDMA-PTSD in MAPS partnerships, and psilocybin safety studies.

Q · 05

Have any Wisconsin cities decriminalised?

No. Madison, Milwaukee, Green Bay, and other Wisconsin municipalities have not adopted independent psilocybin decriminalisation ordinances. Wisconsin carries zero decriminalised cities.

While the federal track advances and state quiet continues

iMicrodosing.com ships lab-verified products within all applicable federal, state, and local laws. For deeper research and clinical context on psilocybin therapy outcomes, imicrodosing.org aggregates the trial literature.